Bioprocess innovation for high-value bioactives

Bioactive innovation engineered for commercial scale.

Shear Biosciences develops, uses and integrates bioprocess technologies to produce efficient, high-value bioactive products, designed for minimal environmental impact, from concept to commercial implementation.

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Home hero. A compact natural still life with one elegant clear glass vial of golden-green botanical extract, a fresh sacred fig/peepal leaf with a long tapering tip, a small tulsi sprig and a single marigold blossom, with one small fresh turmeric section.
  • Solvent-free or low-solventRecovery of high-value compounds wherever the chemistry allows
  • Bioavailable and stableProduct forms designed for performance
  • Lab to plantLaboratory, pilot and commercial-scale development

The next generation of bioactives requires more than extraction.

Commercial success depends on the complete product system: how the bioactive is generated or released, how its structure is preserved or transformed, how it is separated and stabilized, and how the process performs beyond the laboratory. Shear Biosciences brings these decisions together through an application-led development pathway designed around the target product, biological source and intended market. Compounds and extracts from natural sources are the starting point for our R&D. Explore our R&D approach.

Home product pathway. Three physical materials form a simple left-to-right still life: a fresh hibiscus blossom with a few leaves, one small clear glass vessel of golden-green botanical liquid, and a shallow glass dish of olive-gold ingredient powder.
  1. Fresh marigold, neem leaves and turmeric beside a clear botanical sampling dish.01Biological sourceUnderstand the material
  2. A glass filtration setup recovering golden-green extract beside citrus peel.02Targeted recoveryChoose the process
  3. Golden-green formulation samples, a pipette and fine botanical ingredient powder.03Product performanceEngineer the form
  4. A compact stainless-steel processing system with a golden-green sight glass and control panel.04Commercial scaleValidate and transfer

Efficient products, designed for minimal environmental impact

We develop, use or integrate technologies, strategies and processes with one aim: an efficient product. For us, efficient means:

A clean hygienic pipe connection on a simple stainless-steel processing line.

Simple processes

Fewer steps and straightforward operation, from laboratory to plant.

A researcher weighing fresh turmeric on a laboratory balance.

Cost-effective

Processes designed around yield, resource use and realistic production economics.

Clean water flowing into a stainless-steel process vessel.

Solvent-free or low-solvent

Recovery of high-value compounds with little or no solvent, wherever the chemistry allows.

A pale golden-green botanical dispersion swirling through water in a laboratory dish.

Improved bioavailability

Product forms designed for better dispersibility, dissolution and uptake.

A gloved hand sealing an amber ingredient jar for storage.

Stable products

Product forms designed to keep their quality through processing, storage and use.

Rain droplets and morning light on a fresh banana leaf.

Lower environmental impact

Designed to cut energy, water and solvent use, reduce waste and make fuller use of biomass, checked by mass balance.

Core innovation domains

Four domains, combined for each project

We do not run a standard platform. We develop, use or integrate each technology, alone or in combination, around the raw material, the target compound and the application, choosing the most efficient route.

Bioactive Generation overview. Close-up of a small glass culture vessel with a delicate lavender plant shoot and natural pale medium; a carefully positioned lab hand in the distant soft focus background.

Generate

Bioactive Generation

Plant cell culture, enzymatic bioprocessing, fermentation and biotransformation for high-value compounds.

Green Extraction overview. Fresh marigold petals and a pale citrus peel on a small stainless mesh strainer next to a clear flask holding golden-green botanical liquid.

Extract and recover

Green Extraction and Recovery

Hydrodynamic cavitation, ultrasound, live-plant processing, cryogenic methods and low-impact separation.

Bioavailability and Delivery overview. A glass pipette dispensing a single drop of pale golden-green dispersion into a small clear unlabelled formulation vial, with a plain glass weighing dish behind.

Enhance and deliver

Bioavailability and Delivery

Controlled isomerization, amorphization, molecular organization, nanoemulsions and carrier-minimised systems.

Industrial and Circular overview. Wide natural photograph of a neat stainless-steel pilot processing line in a bright modest pilot laboratory, with tidy hygienic pipes and a small vessel.

Scale and circulate

Industrial and Circular Bioprocessing

Process intensification, pilot-to-plant translation, waste-to-value systems and exploration of emerging CO₂-utilisation pathways.

How partners work with us

A scientist positioning a specimen slide under a microscope.

Contract R&D

Focused scientific programmes to solve a defined product or process challenge.

Researchers comparing cream prototypes at a formulation bench.

New Product Development

From opportunity definition and proof of concept to optimized prototype and quality specification.

Colleagues reviewing a technical folder together.

Technology Licensing and Transfer

Transfer of proprietary or jointly developed know-how, supported by documentation, training and implementation guidance.

A process engineer inspecting a stainless-steel pilot installation.

Pilot and Commercial Implementation

Scale-up strategy, pilot trials, equipment definition, engineering coordination, commissioning support and team training.

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Have a biomass, bioactive or bioprocess challenge?

Tell us what you are trying to produce, improve or scale. We will help determine the most appropriate scientific and development pathway, from feasibility through commercial implementation.